Archaeal Proteome Project

The Archaeal Proteome Project (ArcPP) performs a combined and unified analysis of mass spectrometry-based proteomics datasets and provides a database of all reliably identified proteins for a given archaeal species. Datasets can be compared to improve experimental parameters, or to gain biological insights. The ArcPP was initiated for the model archaeon Haloferax volcanii and is currently in the process of expansion to various other archaea.


Schulze S, Adams Z, Cerletti M, De Castro R, Ferreira-Cerca S, Fufezan C, Giménez MI, Hippler M, Jevtic Z, Knüppel R, Legerme G, Lenz C, Marchfelder A, Maupin-Furlow J, Paggi RA, Pfeiffer F, Poetsch A, Urlaub H, Pohlschroder M. The Archaeal Proteome Project advances knowledge about archaeal cell biology through comprehensive proteomics. Nat Commun. 2020 Jun 19;11(1):3145. doi: 10.1038/s41467-020-16784-7. PMID: 32561711; PMCID: PMC7305310.